6/4/2017 0 Comments New Diet Pill Fexaramine Human![]() Newsmax Health reports todays breaking health news, latest health news, health news today, current health news, medical news, health articles, newsmaxhealth.com.The Weight Loss Pill Of The Future (No, We Swear) Helps Diabetics And Obese. A new pill developed by the Salk Institute may be an answer to the giant, out- of- shape question mark that is the American obesity epidemic. Researchers are calling it the “Invisible Meal” because of how it interacts with the body’s digestive system, and if it works as well in humans as it already has in mice, the future of weight loss could see serious turnarounds. Recently published in an issue of Nature Medicine, the findings hinge on a receptor nestled in much of the body’s gut, called the farensoid X receptor, or FXR. A new diet pill that limits its effects to the intestines looks promising in trials on mice. News; Science; Diet pill that makes you feel full proven to keep weight off in mice, scientists say. A new pill developed by the Salk Institute may be an answer to the giant, out-of-shape question mark that is the American obesity epidemic. Researchers are calling it. It turns on when we begin to eat food, helping bile to digest the contents for nutrient absorption. But where previous weight loss pills have failed, due to harmful scattershot FXR targeting or other means, such as outright appetite suppression, researchers believe the new pill’s mechanism avoids these risks. But there are no calories and no change in appetite. It’s intended for the some 2. If scientists can perfect the pill’s effectiveness while minimizing side effects, they hope it can someday replace gastric bypass surgery as a desired means of major weight loss. If mouse models are anything to go by, the future is promising. Over a five- week period, lab mice who took a daily pill of fexaramine, a compound the team developed from the normal drug combination, showed significant weight loss; drops in blood pressure, cholesterol, and blood sugar; and rises in body temperature, which signaled accelerated metabolisms. They also lost significantly more body fat compared to the mice that weren’t on the regimen, and some of the white fat turned to the healthier brown fat that helps burn energy. Why the fexaramine compound works better than the drugs that target FXR in much the same way may have to do with some well- time molecular signaling, the team suggests. 2015 was a fantastic year for science, with some important advances made in cancer research, the environment, engineering and biodiversity. Here are 15 discoveries. This narrowed focus allows the intestines to receive the full brunt of the pill’s effects, without any hazardous collateral damage incurred by other organs or causing the person to gain weight. In future trials, Evans and the team hope to transition the findings from mouse to human models. And to allay any remaining naysayers, the pill wouldn’t be a silver bullet for obesity and diabetes; patients would still need to maintain a healthy balance of diet and exercise — something that hopefully will only get easier as the pounds come off. Source: Fang S, Suh J, Reilly S, et al. Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. Experts say the findings point the way to new diagnostic and treatment approaches.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. Archives
June 2017
Categories |